Product Details
Place of Origin: China
Brand Name: Sunshine
Certification: ISO,COA
Model Number: 439081-18-2
Payment & Shipping Terms
Minimum Order Quantity: Negotiation
Price: Negotiation
Packaging Details: Aluminum Foil Bag, Drum
Delivery Time: 7-15 days
Payment Terms: T/T, L/C, D/A, Western Union
Supply Ability: TON
CAS NO:: |
439081-18-2 |
Appearance :: |
Off-white Solid |
Molecular Formula:: |
C24H25ClFN5O3 |
Molecular Weight:: |
485.94 |
EINECS NO:: |
1308068-626-2 |
MDL NO:: |
MFCD12407405 |
CAS NO:: |
439081-18-2 |
Appearance :: |
Off-white Solid |
Molecular Formula:: |
C24H25ClFN5O3 |
Molecular Weight:: |
485.94 |
EINECS NO:: |
1308068-626-2 |
MDL NO:: |
MFCD12407405 |
Product Description:
Product Name: Afatinib CAS NO:439081-18-2
Synonyms:
Tovok;BIBW2992;
(S)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide;
2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-;
(E/Z)-Afatinib;
Afatinib cis-trans isomer;
2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-, (2E)-;
(S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide;
(2E)-N-(4-[(3-chloro-4-fluorophenyl)amino]-7-{[(3S)-tetrahydrofuran-3-yl]oxy}quinazolin-6-yl)-4-(dimethylamino)but-2-enamide;
Chemical & Physical Properties:
Appearance :Off-white solid.
Assay : ≥99.5%
Density 1.380g/cm3
Boiling Point 676.917ºC at 760 mmHg
Melting Point 100 - 102 °C
Flash Point 363.186ºC
Refractive Index 1.668
BIBW 2992 is an anilino-quinazoline that irreversibly inhibits EGFR and HER2 kinase activity.
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