Product Details
Place of Origin: China
Brand Name: Sunshine
Certification: ISO,COA
Model Number: 1231930-82-7
Payment & Shipping Terms
Minimum Order Quantity: Negotiation
Price: Negotiation
Packaging Details: Aluminum Foil Bag, Drum
Delivery Time: 7-15 days
Payment Terms: T/T, L/C, D/A, Western Union
Supply Ability: TON
CAS NO:: |
1231930-82-7 |
Appearance :: |
Off-white Solid |
Molecular Formula:: |
C28H36F2N8O3S |
Molecular Weight:: |
602.699 |
EINECS NO:: |
N/A |
MDL NO:: |
MFCD25562906 |
CAS NO:: |
1231930-82-7 |
Appearance :: |
Off-white Solid |
Molecular Formula:: |
C28H36F2N8O3S |
Molecular Weight:: |
602.699 |
EINECS NO:: |
N/A |
MDL NO:: |
MFCD25562906 |
Product Description:
Product Name: Abemaciclib mesylate CAS NO:1231930-82-7
Synonyms:
N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine,methanesulfonic acid;
N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine methanesulfonate;
Chemical & Physical Properties:
Appearance :Off-white Solid.
Assay : ≥99.0%
N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine is an CDK4/6 protein kinase inhibitor with potential antitumor effects.
Abemaciclib (LY2835219) (methanesulfonate) is a selective CDK4/6 inhibitor with IC50s of 2 nM and 10 nM for CDK4 and CDK6, respectively.
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