Product Details
Place of Origin: China
Brand Name: Sunshine
Certification: ISO,COA
Model Number: 210421-74-2
Payment & Shipping Terms
Minimum Order Quantity: Negotiation
Price: Negotiation
Packaging Details: Aluminum Foil Bag, Drum
Delivery Time: 7-15 days
Payment Terms: T/T, L/C, D/A, Western Union
Supply Ability: TON
CAS NO:: |
210421-74-2 |
Appearance :: |
White To Off-white Powder |
Molecular Formula:: |
C18H14ClN2NaO6S2 |
Molecular Weight:: |
476.886 |
EINECS NO:: |
606-692-6 |
MDL NO:: |
MFCD11040990 |
CAS NO:: |
210421-74-2 |
Appearance :: |
White To Off-white Powder |
Molecular Formula:: |
C18H14ClN2NaO6S2 |
Molecular Weight:: |
476.886 |
EINECS NO:: |
606-692-6 |
MDL NO:: |
MFCD11040990 |
Product Description:
Product Name: Sitaxsentan sodium CAS 210421-74-2
Synonyms:
Thelin;
Sitax;
Sitaxentan sodium;
sodium,(4-chloro-3-methyl-1,2-oxazol-5-yl)-[2-[2-(6-methyl-1,3-benzodioxol-5-yl)acetyl]thiophen-3-yl]sulfonylazanide;
Chemical & Physical Properties:
Appearance : white to off-white powder
Assay :≥98.0%
Water Solubility:H2O: soluble10mg/mL (clear solution)
Selective endothelin A (ETA) receptor antagonist. Antihypertensive. Used in treatment of chronic heart failure.
Sitaxentan sodium, belongs to thesulfonamide class of endothelin receptor antagonists.Although it has 6,000-fold selectivity for the ETA receptor,clinical trials have not demonstrated a greater efficacyover bosentan. However, it has much lower liver toxicitythan bosentan. The manufacturer is attempting to meetefficacy outcomes set by the FDA, which must be met beforeapproval of sitaxsentan as a therapeutic agent will begranted.
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