Olopatadine Hydrochloride CAS 140462-76-6

Product Description:

Product Name: Olopatadine hydrochloride CAS NO: 140462-76-6

Synonyms:

Dibenz[b,e]oxepin-2-acetic acid, 11-[3-(dimethylamino)propylidene]-6,11-dihydro-, (11Z)-, hydrochloride (1:1);

{(11Z)-11-[3-(Dimethylamino)propylidene]-6,11-dihydrodibenzo[b,e]oxepin-2-yl}acetic acid hydrochloride;

Chemical & Physical Properties:

Appearance : White powder

Assay :≥99.0%

Density:1.22g/cm3

Boiling Point:523℃ at 760 mmHg

Flash Point:270.1℃

Melting Point:242-245℃

Solubility:H2O: ≥20mg/Ml

Olopatadine hydrochloride is a mast cell stabilizer and relatively selective H1 receptor blocker, which can inhibit type I allergic reactions and is mainly used to treat allergic conjunctivitis.

Olopatadine HCl is marketed for topical use to alleviate symptoms of allergic conjunctivitis in humans and is thought to be safe for use in children three years of age and older. Olopatadine, upon topical application in humans, was shown to have very limited systemic absorption. It was detectable in the milk of nursing rats, after topical application, and like most medications should be avoided in pregnant or nursing animals.

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