Avanafil CAS 330784-47-9

Product Description:

Product Name: Avanafil CAS NO: 330784-47-9

Synonyms:

4-[[(3-Chloro-4-Methoxyphen yl)Methyl]Amino]-2-[(2S)-2-(Hydroxymethyl)-1-Pyrrolidinyl]-N-(2-Pyrimidinylmethyl)-5-Pyrimidinecarboxamide;

Chemical & Physical Properties:

Appearance :White powder

Assay :≥98.0%

Density: 1.372g/cm3

Melting Point:150-152℃

Avanafil is a PDE5 inhibitor approved for erectile dysfunction by the FDA on April 27, 2012 and by EMA on June 21, 2013. Avanafil is known by the trademark names Stendra and Spedra and was developed by Vivus Inc. In July 2013 Vivus announced partnership with Menarini Group, which will commercialise and promote Spedra in over 40 European countries plus Australia and New Zealand. Avanaf il acts by inhibiting a specific phosphodiesterase type 5 enzyme which is found in various body tissues, but primarily in the corpus cavernosum pe nis, as well as the retina. Other similar drugs are sildenaf il, tadalaf il and vardenaf il. The advantage of avanaf il is that it has very fast onset of action compared with other PDE5 inhibitors. It is absorbed quickly, reaching a maximum concentration in about 30–45 minutes.

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