2,6-Dimethylpyridine CAS 108-48-5

Product Description:

Product Name: 2,6-Dimethylpyridine CAS NO: 108-48-5

Synonyms:

2,6-Lutidine;

Pyridine, 2,6-dimethyl-;

FEMA 3540

Chemical & Physical Properties:

Appearance: Clear liquid

Assay :≥99.0%

Density: 0.9252

Boiling Point: 143-145℃

Melting Point: -6℃

Flash Point: 33℃

Refractive Index: 1.4966-1.4986

Water Solubility: 40 g/100 mL (20 ℃)

Stability: Stable. Flammable. Incompatible with strong oxidizing agents, acid chlorides, acids, chloroformates. Protect from moisture.

Storage Condition:-20℃

Vapor Pressure: 6.52mmHg at 25℃

TSCA: Yes

Sensitive: Hygroscopic

pKa: 6.65(at 25℃)

Merck: 14,5616

Safety Information:

RTECS: OK9700000

Hazard Class: 3

Safety Statements: S16-S36/37

HS Code: 29333999

Packing Group: III

WGK Germany: 3

RIDADR: UN 1993

Risk Statements: R10; R20/21/22

Hazardous Substances Data: 108-48-5(Hazardous Substances Data)

Toxicity: LD50 orally in Rabbit: 400 mg/kg LD50 dermal Rabbit > 1000 mg/kg

Hazard Codes: Xn, F, Xi

F: 8

Hazard Note: Irritant/Flammable

2,6-Lutidine is a natural heterocyclic aromatic organic compound. It has been isolated from the basic fraction of coal tar and from bone oil. It is a dimethyl substituted derivative of pyridine. It has been detected in waste water from oil shale processing sites and former creosoting facilities. Pyridine, 2,6-dimethyl- has been evaluated for use as a food additive owing to its nutty aroma when present in solution at very low concentrations, however the neat solvent has a pungent, noxious odor.

2,6-Dimethylpyridine is weakly nucleophilic, due to the steric effects of the two methyl groups on the ring nitrogen. It is moderately basic, with a pKa of 6.60. In organic synthesis, 2,6-lutidine is thus widely used as a sterically hindered mild base.

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