Gentamicin Sulfate CAS 1405-41-0 API Active Pharmaceutical Ingredient

Product Description:

Product Name: Gentamicin Sulfate CAS NO: 1405-41-0

Synonyms:

4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-piperidi-ne hydrochloride hydrate;

Piperidi-ne (4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl;

Cyproheptadine hydrochloride;

Chemical & Physical Properties:

Appearance: White to buff-colored powder. Odorless.

Assay :≥99%

Boiling Point: 797.6℃ at 760 mmHg

Melting Point: 218-237℃

Flash Point: 436.2℃

Water Solubility: Soluble in water

Storage Condition: 2-8℃

Stability: Stable under normal temperatures and pressures

Safety Information:

WGK Germany: 2

RTECS: LY2625000

Risk Statements: R42/43

Hazard Code: Xn

HS Code: 2941901000

Hazard Statements: H317-H334

Symbol: GHS08

Signal Word: Danger

Safety Statements: S23-S36/37-S45

Precautionary Statements: P261-P280-P342 + P311

Inhibits protein synthesis by binding to L6 protein of 50S ribosomal subunit. Antibacterial. Antibiotic complex consists of three closely related components, gentamicins C1, C2, C1a, and also gentamicin A which differs from the other members of the complex but is similar to Kanamycin C. Gentamicin C1: R1=R2=CH3 Gentamicin C2: R1=CH3; R2=H Gentamicin C1A: R1=R2=H.

This compound is a complex mixture of the sulfates of gentamycin Cl, gentamycin CIA and gentamycin C2. Pharmaceutical incompatibilites include amphotericin, cephalosporins, erythromycin, heparin, penicillins, sodium bicarbonate, and sulfadiazine sodium. It is used as topical and systemic broad-spectrum antibiotic with bactericidal action; also used in ophthalmic drugs.

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