3-Pyridinecarboxamide CAS 98-92-0

Product Description:

Product Name: 3-Pyridinecarboxamide CAS NO: 98-92-0

Synonyms:

Vitamin B3 (Nicotinamide);

Vitamin PP (Nicotinamide);

Pyridine-3-carboxamide;

Chemical & Physical Properties:

Appearance: White crystalline powder

Assay :≥99.0%

Density: 1.40 g/cm3

Boiling Point: 334℃

Melting Point: 129.5℃

Flash Point: 182℃

Refractive Index: 1.4660 (estimate)

Water Solubility: Soluble, 691g/L (20℃)

Odor: Odorless

Safety Information:

WGK Germany: 1

Symbol: GHS07

Signal Word: Warning

RTECS: QS3675000

Hazard Codes:Xi,T,F

HS Code: 2933399090

Hazard Declaration: H315; H319; H335

Safety Statements: S26-36-37/39-45-36/37-16-7

Caution Statements: P261; P305 + P351 + P338

Risk Statements: R36/37/38-39/23/24/25-23/24/25-11

RIDADR: UN1230 - class 3 - PG 2 - Methanol, solution

Nicotinamide, also known as niacinamide, NAA, and nicotinic amide, is the amide of nicotinic acid (vitamin B3 / niacin). Nicotinamide is a water-soluble vitamin and is part of the vitamin B group. Nicotinic acid, also known as niacin, is converted to nicotinamide in vivo, and, though the two are identical in their vitamin functions, nicotinamide does not have the same pharmacological and toxic effects of niacin, which occur incidental to niacin's conversion. Thus nicotinamide does not reduce cholesterol or cause flushing, although nicotinamide may be toxic to the liver at doses exceeding 3 g/day for adults. In cells, niacin is incorporated into nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP), although the pathways for nicotinic acid amide and nicotinic acid are very similar. NAD+ and NADP+ are coenzymes in a wide variety of enzymatic oxidation-reduction reactions. Commercial production of niacin and niacinamide (several thousand tons annually) is by hydrolysis or aminolysis of 3-cyanopyridine (nicotinonitrile).Small intestinal bacterial overgrowth is one known cause of nicotinamide deficiency.

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