Terazosin Hydrochloride Dihydrate CAS 70024-40-7

Product Description:

Product Name: terazosin hydrochloride dihydrate CAS NO: 70024-40-7

Synonyms:

4-Amino-6,7-dimetho-xy-2-[4-(tetrahydro-2-furoyl)-1-piperazinyl]quinazoline Hydrochloride;

Methanone,[4-(4-aMino-6,7-diMetho-xy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)-,hydrochloride, hydrate (1:1:2);

Terazosin Hydrochloride ImpuritV;

Chemical & Physical Properties:

Appearance: White or off-white crystalline powder

Assay :≥98.0%

Boiling Point: 664.5℃ at 760 mmHg

Melting Point: 215 – 217℃

Solubility: Sparingly soluble in water, slightly soluble in methanol, very slightly soluble in ethanol (96 per cent), practically insoluble in aceto-ne.

Safety Information:

Symbol: GHS07

Signal Word: Warning

Risk Statement: S22

RTECS: TK8046000

Hazard Code: Xn

HS Code: 2934990002

Hazard Statement: H302

Precautionary Statements: P301 + P312 + P330

Toxicity: LD50 in male, female rats (mg/kg): 277, 293 i.v. (Fort)

Terazosin Hydrochloride Dihydrate is an α-1-adrenergic blocker related to prazosin. An alpha-1 adrenoceptor selective antagonist. Terazosin Hydrochloride dihydrate is a selective alpha1-antagonist used for treatment of symptoms of benign prostatic hyperplasia (BPH).Target: Alpha-1 Adrenergic ReceptorTerazosin Hydrochloride dihydrate is an a1-selective blocker. Its inhibitory effect on prostate tumor growth may be the result of antiangiogenic activity. Terazosin Hydrochloride dihydrate is an inhibitor of α1A-AR, α1B-AR, α1D-AR and α2B-AR.

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