Olodaterol Hydrochloride CAS 869477-96-3

Product Description:

Product Name: olodaterol hydrochloride CAS NO: 869477-96-3

Synonyms:

UNII-65R445W3V9;

OLODATEROL HYDROCHLORIDE;

Bi-1744-cl;

Chemical & Physical Properties:

Appearance: Off-White to pale beige solid

Assay :≥99.0%

Exact Mass: 422.16100

Melting Point153-155℃

Storage: Hygroscopic, -20℃ Freezer, under inert atmosphere.

Solubility: DMSO (Slightly), Methanol (Slightly)

Stability: Hygroscopic

Olodaterol hydrochloride was approved for long-term, oncedaily maintenance treatment of chronic obstructive pulmonary disease (COPD) in 2013 in the following countries: Canada, Russia, United Kingdom, Denmark, and Iceland. The drug has been recommended by a federal advisory panel for approval by the FDA. Developed and marketed by Boehringer Ingelheim, olodaterol is a long-acting b2-adrenergic receptor agonist with high selectivity over the b1- and b3-receptors (219- and 1622-fold, respectively). Upon binding to and activating the b2-adrenergic receptor in the airway, olodaterol stimulates adenyl cyclase to synthesize cAMP, leading to the relaxation of smooth muscle cells in the airway. Administered by inhalation using the Respimat® Soft Mist inhaler, it delivers significant bronchodilator effects within five minutes of the first dose and provides sustained improvement in forced expiratory volume (FEV1) for over 24 h. Olodaterol is a long acting β-adrenoceptor agonist used as an inhalation for treating patients with chronic obstructive pulmonary disease (COPD).

If you are interested in our products or have any questions, please feel free to contact us!

Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.