High Purity Adenine Arabinoside CAS 5536-17-4

Product Description:

Product Name: adenine arabinoside CAS NO: 5536-17-4

Synonyms:

Vidarabine;

ara-adenosine;

9H-Purin-6-amine, 9.β.-D-arabinofuranosyl-;

Chemical & Physical Properties:

Appearance: White to off-white crystalline powder

Assay :≥99.0%

Density: 2.08g/cm3

Boiling Point: 676.3℃ at 760mmHg

Melting Point: 260-265℃ (dec.)

Flash Point: 362.8℃

Refractive Index: 1.907

Storage Condition: -20℃

Water Solubility: Soluble in DMF (10 mg/ml), 0.5 M HCl (50 mg/ml), DMSO (53 mg/ml at 25℃), ethanol (<1 mg/ml at 25℃), and water (3 mg/ml at 25℃).

Safety Information:

Symbol: GHS08

Signal Word: Warning

Safety Statements: 36/37-36-26

HS Code: 29349990

Packing Group: II

RIDADR: UN 2811

Risk Statement: R63

Hazard Code: Xn

Hazard Class: 6.1(a)

Hazard Declaration: H361

Caution Statement: P281

Vidarabine (adenine arabinoside) is the stereoisomer of adenosine. This analog of a purine nucleoside exhibits selective activity against the herpes virus. The ribose residue is replaced with an arabinose residue. Like acyclovir, it turns into mono-, di-, and triphosphate in cells infected by a virus, thus inhibiting DNA polymerase, and correspondingly preventing DNA synthesis of the virus approximately 20–40 times more than in “host” cells. It is easily metab[1]olized to a less active, yet nonetheless antiviral compound—arabinosylhypoxanthine. It has been successfully used for herpetic encephalitis, and for complicated shingles. It is used in the form of eye drops for herpetic keratoconjuctivitis. A synonym of this drug is Vira-A. active component of chili peppers, analgesic and therapeutic agent for arthritis, potential prophylactic for type 1 diabetes.

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