Product Details
Place of Origin: China
Brand Name: Sunshine
Certification: ISO,COA
Model Number: 2083627-02-3
Payment & Shipping Terms
Minimum Order Quantity: Negotiation
Price: Negotiation
Packaging Details: Aluminum Foil Bag, Drum
Delivery Time: 7-15 days
Payment Terms: T/T, L/C, D/A, Western Union
Supply Ability: TON
CAS NO:: |
2083627-02-3 |
Appearance:: |
White To Off-white Solid |
Molecular Formula:: |
C17H15N5O3S |
Molecular Weight:: |
369.39800 |
EINECS NO:: |
NA |
MDL NO:: |
NA |
CAS NO:: |
2083627-02-3 |
Appearance:: |
White To Off-white Solid |
Molecular Formula:: |
C17H15N5O3S |
Molecular Weight:: |
369.39800 |
EINECS NO:: |
NA |
MDL NO:: |
NA |
Product Description:
Product Name: EED226 CAS NO: 2083627-02-3
Synonyms:
N-(furan-2-ylmethyl)-8-(4-(methylsulfonyl)phenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine;
MAK683(EED226/Compound 43);
CS-2549;EED226;
Chemical & Physical Properties:
Appearance: White to off-white solid
Assay :≥98.0%
Density: 1.49±0.1 g/cm3 (Predicted)
PKa: 1.19±0.30(Predicted)
Storage Conditions: -20℃
EED226 is an effective and selective with the activity of oral Polycombrepressivecomplex2 (PRC2) inhibitors, H3K27me0Chemicalbookpeptide as substrates, IC50 = 23.4 nM; With mononucleosome as substrate, IC50=53.5nM. It interacts directly with the EED H3K27ME3 binding pocket.
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