Product Details
Place of Origin: China
Brand Name: Sunshine
Certification: ISO,COA
Model Number: 1508250-71-2
Payment & Shipping Terms
Minimum Order Quantity: Negotiation
Price: Negotiation
Packaging Details: Aluminum Foil Bag, Drum
Delivery Time: 7-15 days
Payment Terms: T/T, L/C, D/A, Western Union
Supply Ability: TON
CAS NO:: |
1508250-71-2 |
Appearance:: |
Solid Powder |
Molecular Formula:: |
C26H31ClN6O2 |
Molecular Weight:: |
495.01600 |
EINECS NO:: |
NA |
MDL NO:: |
NA |
CAS NO:: |
1508250-71-2 |
Appearance:: |
Solid Powder |
Molecular Formula:: |
C26H31ClN6O2 |
Molecular Weight:: |
495.01600 |
EINECS NO:: |
NA |
MDL NO:: |
NA |
Product Description:
Product Name: Nazartinib CAS NO: 1508250-71-2
Synonyms:
(R,E)-N-(7-chloro-1-(1-(4-(dimethylamino)but-2-enoyl)azepan-3-yl)-1H-benzo[d]imidazol-2-yl)-2-methylisonicotinamide;
EGF816;
Chemical & Physical Properties:
Appearance: Solid powder
Assay :≥98.0%
Density: 1.28±0.1 g/cm3 (Predicted)
PKa: 11.38±0.43 (Predicted)
Water Solubility: Insoluble
Index of Refraction: 1.643
Soluble: Soluble in DMSO
Storage Condition: Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).
Nazartinib (EGF816, NVS-816) is a covalent, irreversible, selective inhibitor of mutant EGFR. It has nanomolar inhibitory effect on mutant EGFR(L858R, Ex19Del) and T790M. It is more specific for mutant EGFR.
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