Product Details
Place of Origin: China
Brand Name: Sunshine
Certification: ISO,COA
Model Number: 2060571-02-8
Payment & Shipping Terms
Minimum Order Quantity: Negotiation
Price: Negotiation
Packaging Details: Aluminum Foil Bag, Drum
Delivery Time: 7-15 days
Payment Terms: T/T, L/C, D/A, Western Union
Supply Ability: TON
CAS NO:: |
2060571-02-8 |
Appearance:: |
Solid Powder |
Molecular Formula:: |
C18H19F2N5O4 |
Molecular Weight:: |
407.37100 |
EINECS NO:: |
NA |
MDL NO:: |
MFCD31382124 |
CAS NO:: |
2060571-02-8 |
Appearance:: |
Solid Powder |
Molecular Formula:: |
C18H19F2N5O4 |
Molecular Weight:: |
407.37100 |
EINECS NO:: |
NA |
MDL NO:: |
MFCD31382124 |
Product Description:
Product Name: GDC-0077 CAS NO: 2060571-02-8
Synonyms:
(2S)-2-[[2-[(4S)-4-(difluoromethyl)-2-oxo-1,3-oxazolidin-3-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl]amino]propanamide;
Chemical & Physical Properties:
Appearance: Solid powder
Assay :≥98.0%
Solubility: DMSO
Storage: Store in a cool and dry place (or refer to the Certificate of Analysis).
GDC-0077 is an orally available PI3K inhibitor with potential antineoplastic activity. GDC-0077 is extracted from patent WO 2017001645 A1, formula I. GDC-0077 is an orally available and selective PI3K inhibitor (IC50 = 0.038 + 0.003 nM) with > 300-fold selective over other Class I PI3K isoforms. GDC-0077 exerts its activity by binding to the ATP binding site of PI3K, thereby inhibiting the phosphorylation of PIP2 to PIP3.
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Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.
