Product Details
Place of Origin: China
Brand Name: Sunshine
Certification: ISO,COA
Model Number: 181223-80-3
Payment & Shipping Terms
Minimum Order Quantity: Negotiation
Price: Negotiation
Packaging Details: Aluminum Foil Bag, Drum
Delivery Time: 7-15 days
Payment Terms: T/T, L/C, D/A, Western Union
Supply Ability: TON
CAS NO:: |
181223-80-3 |
Appearance:: |
Solid Powder |
Molecular Formula:: |
C26H28N4O3 |
Molecular Weight:: |
444.52600 |
EINECS NO:: |
NA |
MDL NO:: |
NA |
CAS NO:: |
181223-80-3 |
Appearance:: |
Solid Powder |
Molecular Formula:: |
C26H28N4O3 |
Molecular Weight:: |
444.52600 |
EINECS NO:: |
NA |
MDL NO:: |
NA |
Product Description:
Product Name: DEL-22379 CAS NO: 181223-80-3
Synonyms:
N-{3-[(5-metho-xyindol-3-yl)methylene]-2-oxo(1H-benzo[3,4-d]azolidin-5-yl)}-3-piperidylpropanamide;
N-[2,3-Dihydro-3-[(5-metho-xy-1H-ind-ol-3-yl)methylene]-2-oxo-1H-indol-5-yl]-1-piperidinepropanamide;
Chemical & Physical Properties:
Appearance: Solid powder
Assay :≥98.0%
Density: 1.313±0.06 g/cm3 (Predicted)
Boiling Point: 763.9±60.0℃(Predicted)
PKa: 11.84±0.20 (Predicted)
Flash Point: 415.8±32.9℃
Vapor Pressure: 0.0±2.6 mmHg at 25℃
Index of Refraction: 1.697
DEL-22379 is an ERK dimerization inhibitor. DEL-22379 binds to ERK2 easily, and Kd is at low micromolar level, which can be detected even at low nano Chemicalbook concentration. DEL-22379 inhibited the dimerization of ERK2 with an IC50 of about 0.5 μm.
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