Product Details
Place of Origin: China
Brand Name: Sunshine
Certification: ISO,COA
Model Number: 2628280-40-8
Payment & Shipping Terms
Minimum Order Quantity: Negotiation
Price: Negotiation
Packaging Details: Bag,Drum
Delivery Time: 7-15 days
Payment Terms: T/T, L/C, D/A, Western Union
Supply Ability: TON
CAS No:: |
2628280-40-8 |
Appearance:: |
Solid Powder |
Molecular Formula:: |
C23H32F3N5O4 |
Molecular Weight:: |
499.53 |
EINECS NO:: |
605-001-5 |
MDL NO.:: |
N/A |
CAS No:: |
2628280-40-8 |
Appearance:: |
Solid Powder |
Molecular Formula:: |
C23H32F3N5O4 |
Molecular Weight:: |
499.53 |
EINECS NO:: |
605-001-5 |
MDL NO.:: |
N/A |
Product Description:
Product Name: Nirmatrelvir,PF-07321332 CAS 2628280-40-8
Synonyms:
Nirmatrelvir (PF-07321332);
PF07321332(Paxlovid);
(1R,2S,5S)-N-[(1S)-1-cyano-2-[(3S)-2-oxopyrrolidin-3-yl]ethyl]-3-[(2S)-3,3-dimethyl-2-[(2,2,2-trifluoroacetyl)amino]butanoyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide;
Chemical & Physical Properties
Appearance:Solid powder
Assay: 99%+
Boiling point:742.4±60.0℃
Solubility:DMSO : 140 mg/mL (280.26 mM; Need ultrasonic)
Density:1.267±0.06 g/cm3
Pka:10.26±0.46
Application
Paxlovid is a combination antiviral consisting of two tablets.One tablet was Nirmatrelvir (150mg), an inhibitor of the 3CL protease (also known as the main protease, Mpro) of the novel coronavirus.3CL protease is a key protease that hydrolyzes polymeric precursor proteins encoded by RNA to produce functional proteins during coronavirus replication. Nematavir can prevent SARS-CoV-2 coronavirus replication by inhibiting 3CL protease;The other tablet is Ritonavir (100mg), an HIV-1 protease inhibitor and CYP3A4 (cytochrome P450 3A4 enzyme) inhibitor.
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