Product Details
Place of Origin: China
Brand Name: Sunshine
Certification: ISO,COA
Model Number: 2414572-47-5
Payment & Shipping Terms
Minimum Order Quantity: Negotiation
Price: Negotiation
Packaging Details: Bag,Drum
Delivery Time: 7-15 days
Payment Terms: T/T, L/C, D/A, Western Union
Supply Ability: TON
CAS No:: |
2414572-47-5 |
Appearance:: |
Beige To Light Yellow Solid |
Molecular Formula:: |
C29H29ClN6O4 |
Molecular Weight:: |
561.03 |
EINECS NO:: |
N/A |
MDL NO:: |
MFCD514572475 |
CAS No:: |
2414572-47-5 |
Appearance:: |
Beige To Light Yellow Solid |
Molecular Formula:: |
C29H29ClN6O4 |
Molecular Weight:: |
561.03 |
EINECS NO:: |
N/A |
MDL NO:: |
MFCD514572475 |
Product Description:
BDTX-189,CAS 2414572-47-5
Synonyms:
2-Propenamide,N-[4-[[3-chloro-4-(2-pyridinylmethoxy)phenyl]amino]-7-[2-(4-morpholinyl)ethoxy]-6-quinazolinyl]-;Tuxobertinib;
Chemical & Physical Properties
Boiling point:778.0±60.0℃(Predicted)
Density:1.349±0.06 g/cm3(Predicted)
Storage temp:Store at -20℃
Solubility:DMSO:22.56(Max Conc. mg/mL);40.21(Max Conc. mM)
DMF:1.0(Max Conc. mg/mL);1.78(Max Conc. mM)
DMF:PBS (pH 7.2) (1:2):0.3(Max Conc. mg/mL);0.53(Max Conc. mM)
Form:A solid
Pka:12.20±0.43(Predicted)
Uses :
BDTX-189 is mainly used in laboratory organic synthesis and chemical pharmaceutical research and development processes.
BDTX-189 is an effective allosteric inhibitor of EGFR and HER2 carcinogenic mutations. The Kd values of EGFR, HER2, BLK and ChemicalbookRIPK2 are 0.2nM, 0.76nM, 13nM and 1.2nM respectively. BDTX-189 has anticancer activity.
If you are interested in our products or have any questions, please feel free to contact us!
Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.
