Product Details
Place of Origin: China
Brand Name: Sunshine
Certification: ISO,COA
Model Number: 119509-24-9
Payment & Shipping Terms
Minimum Order Quantity: Negotiation
Price: Negotiation
Packaging Details: Bag,Drum
Delivery Time: 7-15 days
Payment Terms: T/T, L/C, D/A, Western Union
Supply Ability: TON
CAS NO:: |
119509-24-9 |
Appearance:: |
White To Off-white Powder |
Molecular Formula:: |
C15H21Cl2NO5 |
Molecular Weight:: |
366.23700 |
EINECS NO:: |
NA |
MDL NO:: |
NA |
CAS NO:: |
119509-24-9 |
Appearance:: |
White To Off-white Powder |
Molecular Formula:: |
C15H21Cl2NO5 |
Molecular Weight:: |
366.23700 |
EINECS NO:: |
NA |
MDL NO:: |
NA |
Product Description:
Product Name: Atpenin A5 CAS NO: 119509-24-9
Synonyms:
(2S,4S,5R)-1-(2,4-Dihydroxy-5,6-dimetho-xy-3-pyridinyl)-2,4-dimethyl-5,6-dichloro-1-hexanone;
3-[(2S,4S,5R)-5,6-Dichloro-2,4-dimethyl-1-oxohexyl]-4-hydroxy-5,6-dimetho-xy-2(1H)-pyridinone;
Atpenin A5 (Synthetic);
Chemical & Physical Properties:
Appearance: White to off-white powder
Assay :≥99.0%
Density: 1.31g/cm3
Boiling Point: 532.6℃at 760 mmHg
Flash Point: 275.9℃
Refractive Index: 1.534
Vapor Pressure: 1.45E-13mmHg at 25℃
Enantioselective total synthesis of atpenin A5, a potent mitochondrial complex II (succinate-ubiquinone oxidoreductase) inhibitor, has been achieved by a convergent approach through a coupling reaction between 5-iodo-2,3,4,6-tetraalkoxypyridine and a side-chain aldehyde. The two key segments were synthesized through ortho-metalation/boronation with (MeO)3B/oxidation with mCPBA, ortho-iodination, halogen dance reaction, Sharpless epoxidation and regioselective epoxide-opening reaction.
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