Oligomycin A CAS 579-13-5

Product Description:

Product Name: Oligomycin A CAS NO: 579-13-5

Synonyms:

(1R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,27R,28S,29R)-22-ethyl-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonaMethyl-3',4',5',6'-tetrahydro-3H,9H,13H-spiro[2,26-dioxabicyclo[23.3.1]nonaco;

(1R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,27R,28S,29R)-22-ethyl-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-3',4',5',6'-tetrahydro-3H,9H,13H-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-pyran]-3,9,13-trione;

MCH 32;

Chemical & Physical Properties:

Appearance: White to off-white powder

Assay :≥99.0%

Density: 1.14g/cm3

Boiling Point: 886.3℃ at 760mmHg

Melting Point: 150-151℃

Flash Point: 252℃

Refractive Index: 1.543

Storage Condition: -20℃

Safety Information:

Hazard Class: 6.1(b)

Safety Statement: 36/37

Packing Group: III

RIDADR: UN 2811

Risk Statements: R22; R68/20/21/22; R20/21/22

Hazard Codes: Xn; T

Oligomycin A is a macrolide with fungicidal activity isolated from Streptomyces species. Oligomycin A is the dominant analogue of a class macrocyclic lactones isolated from selected strains of Streptomyces sp.. Oligomycin A is an inhibitor of mitochondrial F1F0-ATPase. It induces apoptosis in a variety of cell types, makes cells more susceptible to cell death, and also leads to a switch in the death mode from apoptosis to necrosis. Oligomycin A exhibits a broad biological profile including antifungal, antitumour and nematocidal activities.

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