Staurosporine CAS 62996-74-1

Product Description:

Product Name: Staurosporine CAS NO: 62996-74-1

Synonyms:

Staurosporineinsolution;

9,13-Epoxy-1H,9H-diindolo1,2,3-gh:3,2,1-lmpyrrolo3,4-j1,7benzodiazonin-1-one,2,3,10,11,12,13-hexahydro-10-metho-xy-9-methyl-11-(methylamino)-, (9S,10R,11R,13R)-;

Staurosporine, Antibiotic AM-2282;

Chemical & Physical Properties:

Appearance: White to pale yellow solid

Assay :≥99.0%

Density: 1.56 g/cm3

Boiling Point: 677.5℃ at 760 mmHg

Melting Point: 270℃

Storage Condition: 2-8℃

Water Solubility: Soluble in DMSO or ethanol.Soluble in dimethyl sulfoxide , dimethyl formamide, ethyl acetate, hot aceto-ne and ethanol. Slightly soluble in chloroform and methanol. Insoluble in water.

Safety Information:

Safety Statements: S53-S36-S37

Risk Statement: R40

Hazard Codes: Xn; T; Xi

WGK Germany: 2

Staurosporine (antibiotic AM-2282 or STS) is a natural product originally isolated in 1977 from the bacterium Streptomyces staurosporeus. It was the first of over 50 alkaloids to be isolated with this type of bis-indole chemical structure. The chemical structure of staurosporine was elucidated by X-ray analysis of a single crystal and the absolute stereochemical configuration by the same method in 1994.

Staurosporine was discovered to have biological activities ranging from anti-fungal to anti-hypertensive. The interest in these activities resulted in a large investigative effort in chemistry and biology and the discovery of the potential for anti-cancer treatment.

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