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Home > products > API Active Pharmaceutical Ingredient > MonoMethylauristatin F(MMAF) CAS 745017-94-1

MonoMethylauristatin F(MMAF) CAS 745017-94-1

Product Details

Place of Origin: China

Brand Name: Sunshine

Certification: ISO,COA

Model Number: 745017-94-1

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Highlight:
CAS NO::
745017-94-1
Appearance::
Solid Powder
Molecular Formula::
C39H65N5O8
Molecular Weight::
731.96200
EINECS NO::
NA
MDL NO::
NA
CAS NO::
745017-94-1
Appearance::
Solid Powder
Molecular Formula::
C39H65N5O8
Molecular Weight::
731.96200
EINECS NO::
NA
MDL NO::
NA
MonoMethylauristatin F(MMAF) CAS 745017-94-1

Product Description:

Product Name: MonoMethylauristatin F(MMAF) CAS NO: 745017-94-1

 

 

Synonyms:

(2S)-2-[[(2R,3R)-3-metho-xy-3-[(2S)-1-[(3R,5S)-3-metho-xy-5-methyl-4-[methyl-[(2S)-3-methyl-2-[[(2S)-3-methyl-2-(methylamino)butanoyl]amino]butanoyl]amino]heptanoyl]pyrrolidin-2-yl]-2-methylpropanoyl]amino]-3-phenylpropanoic acid;

Monomethyl auristatin phenylalanine;

Monomethylauristatin F;

 

 

Chemical & Physical Properties:

Appearance: Solid powder

Assay :≥99.0%

Density: 1.116±0.06 g/cm3 (20℃ 760 mmHg), Calc.

Water Solubility: Slightly soluble (2.8 g/L) (25℃), Calc.

Boiling Point: 896.8±65.0 ℃(Predicted)

Storage temp.: Sealed in dry,Room Temperature

Vapour Pressure: 0.0±0.3 mmHg at 25℃

Index of Refraction: 1.522

 

 

Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent. It is part of some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab mafodotin and SGN-CD19A. In International Nonproprietary Names for MMAF-antibody-conjugates, the name mafodotin refers to MMAF plus its attachment structure to the antibody.

 

 

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