Product Details
Place of Origin: China
Brand Name: Sunshine
Certification: ISO,COA
Model Number: 169869-90-3
Payment & Shipping Terms
Minimum Order Quantity: Negotiation
Price: Negotiation
Packaging Details: Bag,Drum
Delivery Time: 7-15 days
Payment Terms: L/C, D/A, T/T, Western Union
Supply Ability: TON
CAS NO:: |
169869-90-3 |
Appearance:: |
Light Yellow To Yellow-green Solid |
Molecular Formula:: |
C25H26FN3O7S |
Molecular Weight:: |
531.55300 |
EINECS NO:: |
NA |
MDL NO:: |
NA |
CAS NO:: |
169869-90-3 |
Appearance:: |
Light Yellow To Yellow-green Solid |
Molecular Formula:: |
C25H26FN3O7S |
Molecular Weight:: |
531.55300 |
EINECS NO:: |
NA |
MDL NO:: |
NA |
Product Description:
Product Name: Exatecan Mesylate CAS NO: 169869-90-3
Synonyms:
DX-8951;
Exatecan mesilate;
Exatecan (Mesylate);
Chemical & Physical Properties:
Appearance: Light yellow to yellow-green solid
Assay :≥99.0%
Exatecan mesylate is a semisynthetic, water-soluble derivative of camptothecin with antineoplastic activity. Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting the religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. This agent does not require enzymatic activation and exhibits greater potency than camptothecin and other camptothecin analogs. Exatecan Mesylate (DX8951f) is a topoisomerase I inhibitor with an IC50 value of 2.2 μM (0.975 μg/mL) for cancer research.
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