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Home > products > API Active Pharmaceutical Ingredient > 1-Methylpseudouridine CAS 13860-38-3

1-Methylpseudouridine CAS 13860-38-3

Product Details

Place of Origin: China

Brand Name: Sunshine

Certification: ISO,COA

Model Number: 13860-38-3

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Price: Negotiation

Packaging Details: Bag,Drum

Delivery Time: 7-15 days

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Highlight:
CAS NO::
13860-38-3
Appearance::
White To Pale Pink Powder
Molecular Formula::
C10H14N2O6
Molecular Weight::
258.22800
EINECS NO::
NA
MDL NO::
NA
CAS NO::
13860-38-3
Appearance::
White To Pale Pink Powder
Molecular Formula::
C10H14N2O6
Molecular Weight::
258.22800
EINECS NO::
NA
MDL NO::
NA
1-Methylpseudouridine CAS 13860-38-3

Product Description:

Product Name: 1-Methylpseudouridine CAS NO: 13860-38-3

 

 

Synonyms:

5-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1-methylpyrimidine-2,4-dione;

(-)-1-Methyl-5-(β-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione;

1-Methyl-5-(β-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione;

 

 

Chemical & Physical Properties:

Appearance: White to pale pink powder

Assay :≥99.0%

Density: 1.576g/cm3

Refractive Index: 1.618

 

 

N1-Methylpseudouridine is a modified nucleoside used for enhancing mRNA translation. Incorporation of N1-Methylpseudouridine into mRNA turns off the immune/eIF2α phosphorylation-dependent inhibition of translation, and increases ribosome pausing and density on the mRNA, thus dramatically facilitating the translation process. N1-Methylpseudouridine outperforms several other modified nucleosides (e.g. 5-Methylcytidine) and corresponding combinations in terms of translation capacity.

 

 

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