5-Bromo-7-azaindole CAS 183208-35-7

Product Description:

Product Name: 5-Bromo-7-azaindole CAS NO: 183208-35-7

Synonyms:

7-aza-5-bromoindole;

RW2897;

5-Bromo-1H-pyrrolo[2,3-b]pyridine;

Chemical & Physical Properties:

Appearance: White to yellow Crystalline Powder

Assay :≥99.0%

Density: 1.77 g/cm3

Melting Point: 169-179℃

Boiling Point: 311.3±22.0℃ at 760 mmHg

Flash Point: 142.1±22.3℃

Vapour Pressure: 0.0±0.6 mmHg at 25℃

Refractive Index: 1.728

Safety Information:

Safety Statements: S26-S39

HS Code: 2933990090

Risk Statements: R22; R41

Hazard Code: Xn

Symbol: GHS05 GHS07

Signal Word: Danger

Hazard Statements: H302-H318

Precautionary Statements: P280-P305 + P351 + P338

7- azindole is an important class of compounds, similar to indoles and purines in structure. Its derivatives have been widely used in medical research because of their potential biological and medicinal value by inhibiting the activity of various proteases. 5 - bromine - 7 - nitrogen impurity indole is developed a new antitumor drug intermediates, although now has a variety of synthesis of 5 - bromine - 7 - nitrogen impurity indole method, such as 2 - aminopyridine as raw material, through bromination, coupling, n-cyclohexylmaleimide, but its reaction process is multifarious, need a lot of bromide, cost is too high, and the reaction yield is low, not suitable for large-scale industrial production. 5-bromo-7-azazindole is the intermediate of laboratory organic synthesis and chemical medicine research and development, mainly used as the intermediate of virofenil, ABT199.

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