Androsterone CAS 53-41-8

Product Description:

Product Name: Androsterone CAS NO: 53-41-8

Synonyms:

5alpha-Androstane-3alpha-ol-17-one;

3alpha-Hydroxy-5alpha-androstan-17-one;

Atromide ICI;

Chemical & Physical Properties:

Appearance: White granules

Assay :≥99.0%

Density: 1.085g/cm3

Boiling Point: 413.1℃ at 760mmHg

Melting Point: 180-185℃

Flash Point: 176.4℃

Refractive Index: 1.536

Stability: Stable under normal temperatures and pressures.

Storage Condition: -20℃

Safety Information:

RTECS: BV8053000

Safety Statements: S22; S24/25

WGK Germany: 3

Androsterone, or 3α-hydroxy-5α-androstan-17-one, is an endogenous steroi-d hormone, neurosteroi-d, and putative pheromone. It is a weak andro-gen with a potency that is approximately 1/7th that of testostero-ne. In addition, it can be converted to dihydrotestoster-ne (DHT) from 3α-hydroxysteroi-d dehydrogenase and 17β-hydroxysteroi-d dehydrogenase, bypassing conventional intermediates such as androstenedione and testostero-ne, and as such, can be considered to be a metabolic intermediate in its own right. Androsterone is also known to be an inhibitory androstane neurosteroi-d, acting as a positive allosteric modulator of the GABAA receptor, and possesses anticonvulsant effects. The unnatural enantiomer of androsterone is more potent as a positive allosteric modulator of GABAA receptors and as an anticonvulsant than the natural form. Androsterone's 3β-isomer is epiandrosterone, and its 5β-epimer is etiocholanolone.

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