17a-Hydroxyprogesterone Acetate CAS 302-23-8

Product Description:

Product Name: 17a-Hydroxyprogesterone acetate CAS NO: 302-23-8

Synonyms:

17α-Acetoxyprogesterone;

ProgesteroneAcetate;

4-Pregnen-17α-ol-3,20-dione acetate;

Chemical & Physical Properties:

Appearance: White Powder

Assay :≥99.0%

Density: 1.14 g/cm3

Boiling Point: 490.2℃ at 760 mmHg

Melting Point: 249-250℃

Flash Point: 211.6℃

Refractive Index: 1.542

Safety Information:

RTECS: TU5074000

Safety Statements: S22; S24/25; S45

WGK Germany: 3

RIDADR: UN 2811 6

Risk Statement: R40

Hazard Code: Xn

Hydroxyprogesterone acetate (HPA) (INN) (brand name Prodox), or 17α-hydroxyprogesterone acetate (17-OHPA), also known as acetoxyprogesterone, is a synthetic, steroidal, orally-active progestin which was discovered by Upjohn in the 1950s and, in 1960, was marketed for use in veterinary medicine. It is a derivative of progesterone and the acetate ester of 17-hydroxyprogesterone, and is a parent compound of a number of progestins, including chlormadinone acetate, cyproterone acetate, medroxyprogesterone acetate, and megestrol acetate.

Hydroxyprogesterone acetate is of relatively low potency as a progestogen, which may explain its limited relative use. It is 100-fold less potent than medroxyprogesterone acetate, 400-fold less potent than chlormadinone acetate, and 1200-fold less potent than cyproterone acetate.

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