Faropenem Sodium Hemipentahydrate CAS 106560-14-9

Product Description:

Product Name: Faropenem sodium hemipentahydrate CAS NO: 106560-14-9

Synonyms:

6alpha-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylic acid;

(+)-(5R,6S)-6-[(1R)-1-Hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furyl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid;

Chemical & Physical Properties:

Appearance: Light yellow powder

Assay :≥99.0%

Density: 1.56g/cm3

Boiling Point: 570.2℃ at 760 mmHg

Flash Point: 298.7℃

Refractive Index: 1.668

Vapor Pressure: 2.23E-15mmHg at 25℃

Safety Information:

Risk Statements: R20/21/22

Farom was launched in Japan for use as an antibiotic against common respiratory tract pathogens. It can be prepared by several related routes of about seven steps starting with tetrahydrofuran-2-thiocarboxylic acid and a silylated azetidinone. It is a broad spectrum oral penem antibiotic that is β-lactamase stable. Farom is the most active β-lactam against anaerobes (more than cefaclor, cefixime and amoxicillin) but also has activity against Gram-positive, Gram-negative and enterobacteriaceae. It is equally active against strains carrying plasmid and chromosome mediated β-lactamases. The short plasma elimination half-life is the result of hydrolysis by renal dehydropeptidase. It is more stable to hydrolysis by extended spectrum β-lactamases than some second and third generation cephalosporins.

If you are interested in our products or have any questions, please feel free to contact us!

Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.