4-Fluorobenzylamine CAS 140-75-0

Product Description:

Product Name: 4-Fluorobenzylamine CAS NO: 140-75-0

Synonyms:

p-FluorobenzeneMethanaMine;

(4-Fluorophenyl)methanamine;

Benzenemethanamine, 4-fluoro-;

Chemical & Physical Properties:

Appearance: Clear, colorless liquid

Assay :≥99.0%

Density: 1.09

Boiling Point: 183℃

Flash Point: 66℃

Refractive Index: 1.5117

Stability: Stable under normal temperatures and pressures.

Storage Condition: Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area.

Vapor Pressure: 0.134mmHg at 25℃

Safety Information:

Hazard Class: 8

Safety Statements: S36/39

HS Code: 2921499090

Packing Group: III

WGK Germany: 3

RIDADR: UN 2735 8/PG 2

Risk Statement: R34

Hazard Code: C

A benzylamine derivative as a potassium channel blocking agent. N- (4-fluorophenyl) phthalimide 25.5g(0.1mol) and 25ml anhydrous ethanol were added into a 100ml reaction flask, followed by 6.3g(0.1mol) of 80% hydrazine hydrate solution, and heated reflux 0.5g. Add excessive hydrochloric acid to decompose the precipitated white precipitate. After cooling, add an appropriate amount of water to stir and filter. The filtrate was neutralized with NaOH solution and extracted with ethyl e-ther. The ethyl e-ther extract was dried and then steamed to remove the ethyl e-ther. The fractions of 44-46℃ (67kPa) were collected by vacuum distillation to obtain 7.1g p-fluorobenzylamine in yield of 56.5%.

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