DESONIDE CAS 638-94-8

Product Description:

Product Name: DESONIDE CAS NO: 638-94-8

Synonyms:

(11b,16a)-11,21-dihydroxy-16,17-((1-methylethylidene)bis(oxy))-pregna-1,4-diene-3,20-dione;16-alpha-hydroxyprednisole-16,17-acetonide;

17-acetonide,16-alpha-hydroxy-prednisolone-1;

Chemical & Physical Properties:

Appearance:White to white like solid

Assay :≥99.0%

Density: 1.3 g/cm3

Boiling Point: 580.1℃ at 760 mmHg

Melting Point: 274 – 275℃

Flash Point: 196.9℃

Refractive Index: 1.598

Storage Condition: Refrigerator

Safety Information:

HS Code: 2937210000

Anti-inflammatory. Desonide has also been found as an impurity in budesonide. Desonide is a nonfluorinated corticostero-id anti-inflammatory agent used topically for dermatoses.Target: Glucocorticoid ReceptorDesonide is a low-potency topical corticostero-id that has been used for decades in the treatment of stero-id-responsive dermatoses. Desonide induced significant colorimetric improvement compared with placebo. A good to excellent response was achieved in 30% for desonide, and 6% for placebo. Decreased pigmentation in the desonide-treated axillae was associated with recovery of disruption at the basal membrane. Desonide showed depigmenting properties in women with axillary hyperpigmentation. Given the favorable safety profile of all other desonide preparations and their utility as a low potency corticostero-id, desonide foam promises to be a useful addition to the armamentarium, when other desonide vehicles might be less acceptable.

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