Budesonide CAS 51333-22-3

Product Description:

Product Name: Budesonide CAS NO: 51333-22-3

Synonyms:

16,17-Butylidenebis(oxy)-11,21-dihydroxypregna-1,4-diene-3,20-dione;

Budesonide,(11β,16α)-16,17-[Butylidenebis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione;

(11-beta,16-alpha)-16,17-(butylidenebis(oxy))-11,21-dihydroxypregna-1,4-dien;

Chemical & Physical Properties:

Appearance: White solid

Assay :≥99.0%

Density: 1.27 g/cm3

Boiling Point: 599.7℃ at 760mmHg

Melting Point: 221-232℃ (dec.)

Flash Point: 201.8℃

Refractive Index: 1.592

Stability: Stable at normal temperatures and pressures.

Storage Condition: Store at RT

Vapour Pressure: 0.0±3.9 mmHg at 25℃

Safety Information:

RTECS: TU3723000

Safety Statements: S22-S36

HS Code: 29372900

WGK Germany: 3

Risk Statement: R40

Hazard Code: Xn

Budesonide (BUD), sold under the brand name Pulmicort among others, is a stero-id medication. It is available as an inhaler, pill, and nasal spray. The inhaled form is used in the long term management of asthma and chronic obstructive pulmonary disease (COPD). The nasal spray is used for allergic rhinitis and nasal polyps. The pills in a delayed release form may be used for inflammatory bowel disease including Crohn's disease, ulcerative colitis and microscopic colitis.

Common side effects with the inhaled form include respiratory infections, cough, and headaches. Common side effects with the pills include feeling tired, vomiting, and joint pains. Serious side effects include an increased risk of infection, loss of bone strength, and cataracts. Long term use of the pill form may cause adrenal insufficiency. Stopping the pills suddenly following long term use may therefore be dangerous. The inhaled form is generally safe in pregnancy. Budesonide is mainly a glucocorticoid.

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