TAPS CAS 29915-38-6 Molecular Formula C7H17NO6S Buffer Chemical

Product Description:

Product Name: TAPS CAS 29915-38-6

Synonyms:

N-[Tris(hydroxymethyl)metyl]-3-aminopropanesulfonic acid;

3-((1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl)amino)propane-1-sulfonic acid;

Chemical & Physical Properties:

Appearance: white crystalline powder

Assay :≥99.0%

Melting point: 230-235℃

Flash point:110℃

Density: 1.43 g/mL

Safety Info

Safety Statements: S22; S24/25; S36; S26

HS Code:2922509090

WGK Germany:3

Risk Statements:R36/37/38

Hazard Codes:Xi

TAPS is used to make buffer solutions. It has a pKa value of 8.44 (ionic strength I=0, 25°C). It can be used to make buffer solutions in the pH range 7.7–9.1.

The pH (and pKa at I≠0) of the buffer solution changes with concentration and temperature, and this effect may be predicted using online calculators. Binds Co(II), Ni(II).

3-[tris(hydroxymethyl)methylamino]-1-propanesulfonic acid can be used as a zwitterionic buffer in the fields of biochemistry and molecular biology. In biochemical experimental projects, it can be used as an important pH stabilizer, usually mixed with weak acids and their conjugate bases to obtain an appropriate pH.

The reaction between 3-[tris(hydroxymethyl)methylamino]-1-propanesulfonic acid and the vast majority of organisms occurs under neutral conditions, requiring a pH value between 6 and 8. At the same time, the effective buffering range of the buffer should also be specified between 6-8, and it is necessary to ensure that the pH form of the buffer reagent cannot chelate with certain metal chemical ions.

In addition, in the field of clinical diagnosis, 3-[tris(hydroxymethyl)methylamino]-1-propanesulfonic acid is also commonly used as a biological buffering agent. Usually used in biochemical diagnostic kits, PCR diagnostic kits, DNA/RNA extraction kits, and other kits.

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