Product Details
Place of Origin: China
Brand Name: Sunshine
Certification: ISO,COA
Model Number: 1194506-26-7
Payment & Shipping Terms
Minimum Order Quantity: negotiation
Price: negotiation
Packaging Details: bag;Drum
Delivery Time: 7-15 days
Payment Terms: T/T, D/A, L/C, Western Union
Supply Ability: KG
CAS NO:: |
1194506-26-7 |
Appearance:: |
White To Off-white Powder |
Molecular Formula:: |
C21H19N3O5 |
Molecular Weight:: |
393.39 |
EINECS NO:: |
962-485-3 |
MDL NO:: |
N/A |
CAS NO:: |
1194506-26-7 |
Appearance:: |
White To Off-white Powder |
Molecular Formula:: |
C21H19N3O5 |
Molecular Weight:: |
393.39 |
EINECS NO:: |
962-485-3 |
MDL NO:: |
N/A |
Product Description:
Product Name: fruquintinib CAS 1194506-26-7
Synonyms:
6-(6,7-dimethoxyquinazolin-4-yl)oxy-N,2-dimethyl-1-benzofuran-3-carboxamide;
Chemical & Physical Properties:
Appearance: white to off-white powder
Assay: ≥ 99.0%
Boiling point: 600.5℃ (Predicted)
Density: 1.302g/cm3
Solubility: Soluble in DMSO (up to 5 mg/ml).
Uses
Fruquintinib (HMPL-013) is a highly selective VEGFR-1/2/3 tyrosine kinase inhibitor. It was approved by the FDA on 8 November 2023 for the treatment of adult patients with metastatic colorectal cancer. and these patients had previously received fluoropyrimidine, oxaliplatin and irinotecan chemotherapy, anti-vascular endothelial growth factor therapy, and anti-epidermal growth factor receptor (EGFR) therapy. Fruquintinib has also been shown to improve cognitive deficits and pathological changes in a mouse model of cerebral amyloid angiopathy (CAA).
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