Doxylamine Succinate CAS 562-10-7 API Active Pharmaceutical Ingredient

Product Description:

Product Name: Doxylamine succinate CAS NO: 562-10-7

Synonyms:

2-(alpha-(2-(dimethylamino)ethoxy)-alpha-methylbenzyl)-pyridinsuccinate(1;

2-(alpha-(2-dimethylaminoethoxy)-alpha-methylbenzyl)pyridinesuccinate;

2-dimethylaminoethoxyphenylmethyl-2-picolinesuccinate;alsadorm;

Chemical & Physical Properties:

Appearance: White to light cream powder

Assay :≥99.0%

Density: 1.043g/cm3

Boiling Point: 364.9℃ at 760 mmHg

Melting Point: 103 – 108℃

Flash Point: 174.5℃

Stability: Stable, but may be light sensitive. Incompatible with strong oxidizing agents, acids, bases.

Storage Condition: Refrigerator

Safety Information:

Safety Statements: S26; S36/37

Risk Statements: R22; R36/37/38

Hazard Codes: Xn,T,F

Hazard Declaration: H302; H312; H332

Signal Word: Warning

Symbol: GHS07

Caution Statement: P280

H1 Histamine receptor antagonist. Antihistaminic; sedative; hypnotic. The acid succinate salt (bisuccinate)of doxylamine, 2-[ -[2-(dimethylamino)ethoxy]- -methylbenzyl]pyridine bisuccinate (Decapryn Succinate), isa white to creamy-white powder with a characteristic odor.It is soluble in water (1:1), alcohol (1:2), and chloroform(1:2). A 1% solution has a pH of about 5.Doxylamine succinate is comparable in potency todiphenhydramine. It is indicated for the relief of seasonalrhinitis symptoms, but is also used as a nighttime sedative.Concurrent use of alcohol and other CNS depressantsshould be avoided.

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