N-(3-chloro-4-fluorophenyl)-7-Metho-xy-6-nitroquinazolin-4-aMine CAS 179552-74-0

Product Description:

Product Name: N-(3-chloro-4-fluorophenyl)-7-Metho-xy-6-nitroquinazolin-4-aMine CAS NO: 179552-74-0

Synonyms:

3-Chloro4-fluoro-phenyl-(7-metho-xy-6-nitro-quinazoline-4-yl)-amine;

4-(3-chloro-4-fluoroanilino)-7-metho-xy-6-nitroquinazoline;

4-(3-chloro-4-fluorophenylamino)-6-nitro-7-metho-xyquinazoline;

Chemical & Physical Properties:

Appearance: Solid

Assay :≥99.0%

Density: 1.529±0.06 g/cm3(Predicted)

Boiling point: 515.5±50.0℃(Predicted)

storage temp.: Keep in dark place,Inert atmosphere,Room temperature

pka: 5.07±0.70(Predicted)

Flash Point: 265.6±0.0℃

Vapour Pressure: 0.0±0.0 mmHg at 25℃

Index of Refraction: 1.696

Safety Information:

Signal Word: Warning

Hazard Statements: H302-H315-H319-H335

Precautionary Statements: P261-P305+P351+P338

N-(3-Chloro-4-fluorophenyl)-7-metho-xy-6-nitroquinazolin-4-amine is a useful synthetic intermediate in the synthesis of Afatinib; an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.

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