Dofetilide CAS 115256-11-6

Product Description:

Product Name: Dofetilide CAS NO: 115256-11-6

Synonyms:

beta-((p-Methanesulfonamidophenethyl)methylamino)methanesulfono-p-phenetidide;

Methanesulfonamide, N-(4-(2-(methyl(2-(4-((methylsulfonyl)amino)phenoxy)ethyl)amino)ethyl) phenyl);

Tikosym;Methyl[2-[4-(methylsulfonylamino)phenoxy]ethyl][4-(methylsulfonylamino)phenethyl]amine;

Chemical & Physical Properties:

Appearance: Off-white or yellowish crystalline powder

Assay :≥99.0%

Density: 1.344 g/cm1.344 g/cm3

Boiling Point: 614.1℃ at 760 mmHg

Melting Point: 147-149℃

Flash Point: 325.2℃

Refractive Index: 1.613

Storage Condition: Store in original container in a cool dark place.

Vapor Pressure: 5.13E-15mmHg at 25℃

Safety Information:

Safety Statements: S26; S37/39

Risk Statements: R36/37/38

Hazard Code: Xi

Symbols: GHS07, GHS08

Caution Statements: P201; P308 + P313

Signal Word: Danger

Hazard Declaration: H302; H360

Dofetilide is a class III antiarrhythmic agent. It is marketed under the trade name Tikosyn by Pfizer, and is available in the United States in capsules containing 125, 250, and 500 µg of dofetilide. It is not available in Europe or Australia.Due to the pro-arrhythmic potential of dofetilide, it is only available by prescription from physicians who have undergone specific training in the risks of treatment with dofetilide. In addition, it is only available by mail order or through specially trained local pharmacies.

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