Clorsulon CAS 60200-06-8

Product Description:

Product Name: Clorsulon CAS NO: 60200-06-8

Synonyms:

4-amino-6-(trichloroethenyl)-3-benzenedisulfonamide;

curatrem;

keluosuolong;

Chemical & Physical Properties:

Appearance: White to off-white crystalline powder

Assay :≥99.0%

Density: 1.8 g/cm3

Boiling Point: 651.7℃ at 760 mmHg

Melting Point: 200 – 207℃

Flash Point: 348℃

Refractive Index: 1.664

Storage Condition: 0-6℃

Safety Information:

RTECS: CZ9090000

HS Code: 2935009090

Safety Statements: S24/25

WGK Germany: 2

Clorsulon is used in the treatment of Fasciola hepatica infections in calves and sheep.Target: AntiparasiticClorsulon is a competitive inhibitor of both 3-phosphoglycorate and ATP and had a Ki of 0.29 mM, inhibits glucose utilization and acetate and propionate formation by mature Fasciola hepatica in vitro. Clorsulon (a single dose of 15 mg/kg) is effective in removing over 90% of immature Fasciola hepatica from sheep (6 weeks after infection) and calves (8 weeks after infection). A 2.5 mg/kg dose removed over 90% of mature (16 weeks old) liver fluke from sheep. Clorsulon causes severe disruption to the tegument and gut of Fasciola hepatica after in vivo incubation.

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