Etodolac CAS 41340-25-4

Product Description:

Product Name: Etodolac CAS NO: 41340-25-4

Synonyms:

1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid;

Tedolan;

Zedolac;

Chemical & Physical Properties:

Appearance: Crystalline solid

Assay :≥99.0%

Density: 1.193 g/cm3

Boiling Point: 507.9℃ at 760 mmHg

Melting Point: 145-148℃

Flash Point: 260.9℃

Stability: Stable at normal temperatures and pressures.

Storage Condition: 2-8℃

Safety Information:

RTECS: UQ0360000

Hazard Class: 6.1(b)

Safety Statements: S22-S36-S45

HS Code: 2934999090

WGK Germany: 3

Packing Group: III

RIDADR: 3249

Risk Statements: R23/24/25; R40

Hazard Code: T

Etodolac is a non-steroidal anti-inflammatory compound that is a non-selective inhibitor of COX (IC50=53.5 nM)IC50 value: 53.5 nMTarget: COX1; COX2Post-marketing studies demonstrated that etodolac inhibition of cyclooxygenase is somewhat COX-2 selective similar to celecoxib and other "COX-2 inhibitors." Unlike rofecoxib, both etodolac and celecoxib can fully inhibit COX-1 and are designated as having "preferential selectivity" toward COX-2. The (inactive against COX) r-enantiomer of etodolac inhibits beta-catenin levels in hepatoma cells.

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