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Home > products > Chemical Intermediates > 1-Boc-3-(cyanomethylene)azetidine CAS 1153949-11-1

1-Boc-3-(cyanomethylene)azetidine CAS 1153949-11-1

Product Details

Place of Origin: China

Brand Name: Sunshine

Certification: ISO,COA

Model Number: 1153949-11-1

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Highlight:
CAS NO::
1153949-11-1
Appearance::
Solid
Molecular Formula::
C10H14N2O2
Molecular Weight::
194.23000
EINECS NO::
831-421-5
MDL NO::
NA
CAS NO::
1153949-11-1
Appearance::
Solid
Molecular Formula::
C10H14N2O2
Molecular Weight::
194.23000
EINECS NO::
831-421-5
MDL NO::
NA
1-Boc-3-(cyanomethylene)azetidine CAS 1153949-11-1

Product Description:

Product Name: 1-Boc-3-(cyanomethylene)azetidine CAS NO: 1153949-11-1

 

 

Synonyms:

3-Cyanomethylene-azetidine-1-carboxylic acid tert-butyl ester;

tert-butyl 3-(cyanoMethylene)azetidine-1-carboxylate;

P-Hydroxy phenyl butanone (Raspberry ketone);

 

 

Chemical & Physical Properties:

Appearance: Solid

Assay :≥99.0%

Density: 1.215

Boiling Point: 309.7±35.0℃(Predicted)

storage temp.: Inert atmosphere,2-8℃

pka: -1.88±0.20(Predicted)

Flash Point: 141.1±25.9℃

Vapour Pressure: 0.0±0.7 mmHg at 25℃

Index of Refraction: 1.578

 

 

Safety Information:

HS Code: 2933990090

RIDADR: UN 3439 6.1/PG III

Hazard Class: 6.1

Packing Group: III

 

 

1-(tert-Butoxycarbonyl)-3-(cyanomethylene)azetidine is used in the synthesis of baricitinib via Horner-Emmons reaction of tert-butyl-oxoazetidine-carboxylate followed by sulfonamidation, nucleophilic addition. and subsequent Suzuki-coupling reaction.

 

 

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