White To Beige Solid Benazepril CAS 86541-75-5

Product Description:

Product Name: Benazepril CAS NO: 86541-75-5

Synonyms:

Benazepril [INN:BAN];

2-[(3S)-3-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-2-oxo-4,5-dihydro-3H-1-benzazepin-1-yl]acetic acid;

(3S)-1-(carboxymethyl)-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-1H-[1]benzazepin-2-one;

Chemical & Physical Properties:

Appearance:White to beige solid

Assay :≥99.0%

Density: 1.26g/cm3

Boiling Point: 691.2℃ at 760 mmHg

Melting Point: 148 – 149℃

Flash Point: 371.8℃

Refractive Index: 1.607

Storage Condition: Store in original container in a cool dark place.

Vapor Pressure: 4.69E-20mmHg at 25℃

Safety Information:

Safety Statements: S22-S24/25

Benazepril, brand name Lotensin (Novartis), is an ACE inhibitor used primarily in treatment of hypertension, congestive heart failure, and heart attacks, and also in preventing the renal and retinal complications of diabetes.

ACE inhibitors relax blood vessels, and decrease blood volume, which lowers blood pressure and decreases oxygen demand from the heart. They inhibit angiotensin-converting enzyme, which is part of the renin–angiotensin–aldosterone system.

Benazepril is a prodrug which is metabolized by the liver into its active form benazeprilat via cleavage of the drug's ester group.

If you are interested in our products or have any questions, please feel free to contact us!

Products under patent are offered for R & D purpose only. However, the final responsibility lies exclusively with the buyer.