Metoclopramide Hydrochloride CAS 54143-57-6

Product Description:

Product Name: Metoclopramide hydrochloride CAS NO: 54143-57-6

Synonyms:

MetoclopraMide HCI;

Gastromax;

Benzamide,4-amino-5-chloro-N-(2-(diethylamino)ethyl)-2-metho-xy-,monohydrochloride,monohydrate;

Chemical & Physical Properties:

Appearance:White to white like solid

Assay :≥99.0%

Boiling Point: 418.7℃ at 760mmHg

Flash Point: 207℃

Water Solubility: It is very soluble in water, easily soluble in ethyl alcohol, slightly soluble in dichloromethane.

Sensitive: Light Sensitive

Safety Information:

WGK Germany: 3

HS Code: 2924296000

Metoclopramide (Reglan) stimulates upper GI tract motility and has both central and peripheral actions. Centrally, it is a dopamine antagonist, an action that is important both for its often desirable antiemetic effect and other less desirable effects. Peripherally, it stimulates the release of intrinsic postganglionic stores of acetylcholine and sensitizes the gastric smooth muscle to muscarinic stimulation. The ability of metoclopramide to antagonize the inhibitory neurotransmitter effect of dopamine on the GI tract results in increased gastric contraction and enhanced gastric emptying and small bowel transit.

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