Crystalline Powder Clozapine Clozapine CAS 5786-21-0

Product Description:

Product Name: Clozapine CAS NO: 5786-21-0

Synonyms:

5H-Dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-methyl-1-piperazinyl)-;

Chemical & Physical Properties:

Appearance: A yellow, crystalline powder, very slightly soluble in water

Assay :≥99.0%

Density: 1.31 g/cm3

Boiling Point: 477.8℃ at 760 mmHg

Melting Point: 182-185℃

Flash Point: 242.8℃

Refractive Index: 1.681

Stability: Stable at normal temperatures and pressures.

Storage Condition: Keep tightly closed.

Safety Information:

RTECS: HP1750000

Hazard Class: 6.1(b)

Safety Statement: S26

HS Code: 2933990090

WGK Germany: 3

Packing Group: III

RIDADR: UN 2811 6

Risk Statements: R22; R36/37/38

Hazard Codes: Xi,Xn,T,F

Hazard Declaration: H301; H341; H361

Signal Word: Danger

Caution Statements: P281; P301 + P310

Symbols: GHS06, GHS08

Clozapine (HF 1854) is an antipsychotic used to treat schizophrenia. Clozapine is a potent antagonist of dopamine and a number of other receptors, with a Ki of 9.5 nM for M1 receptor. It is used for treating acute, chronic mania. It can be used to stabilize the emotion of human. It has good efficacy on treating symptoms like, vagrancy, sleep disorder, sadness, panic, tiredness, easy to be ill, sudden violence, and anger. It can be used for treating mental retardation-caused behavioral disorders such as linguistic disorder, poor presentation ability, poor thought and mental ability, lack of abstraction, generalization ability, low perception, narrow perception range, being difficult to distinguish small differences in body shape, size and color, lack of concentration, narrow attention range, poor memory, slow memorizing and reproducing inaccurately, na?ve behavior, immaturity, emotional instability, lack of self-control and impulsiveness, frequently being timid, withdrawn, shy, asymmetrical shape, uncoordinated movements, poor flexibility, performance, or hyperactivity, destruction, aggression.

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