Ribavirin CAS 36791-04-5 with C8H12N4O5 and MFCD00058564

Product Description:

Product Name: Ribavirin CAS NO: 36791-04-5

Synonyms:

1-(β-D-Ribofuranosyl)-1,2,4-triazole-3-carboxamide;

Nucleosides, Nucleotides & Related Reagents;

Chemical & Physical Properties:

Appearance: Colourless Solid

Assay :≥99.0%

Density: 2.08 g/cm3

Boiling Point: 639.8℃ at 760 mmHg

Melting Point: 174-176℃

Flash Point: 340.7℃

Refractive Index: -36 ° (C=1, H2O)

Storage Condition: 2-8℃

Water Solubility: >=10 g/100 mL at 19℃

Safety Information:

Hazard Class: 9

Safety Statements: S53-22-45-37/39-26

HS Code: 2933290090

WGK Germany: 3

Packing Group: II

RIDADR: UN 3152 9/PG 2

Risk Statement: R61

Hazard Codes: Xi,T

Signal Word: Danger

Hazard Declaration: H360

Symbol: GHS08

Caution Statements: P201; P308 + P313

Ribavirin is an anti-viral drug used for severe RSV infection; hepatitis C infection, including if persistent, and often in combination with peginterferon alfa-2b or peginterferon alfa-2a; as well as some other viral infections.

It is a guanosine (ribonucleic) analog used to stop viral RNA synthesis and viral mRNA capping, thus, it is a nucleoside inhibitor. Ribavirin is a prodrug, which when metabolized resembles purine RNA nucleotides. In this form it interferes with RNA metabolism required for viral replication. How it exactly affects viral replication is unknown; many mechanisms have been proposed for this but none of these has been proven to date. Multiple mechanisms may be responsible for its actions.

Ribavirin was first made in 1972. It is on the World Health Organization's List of Essential Medicines, the most important medication needed in a basic health system.

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