Olanzapine CAS 132539-06-1 with Molecular Weight of 312.43300

Product Description:

Product Name: Olanzapine CAS NO: 132539-06-1

Synonyms:

2-Methyl-4-(4-methylpiperazin-1-yl)-10H-benzo[b]thieno[2,3-e][1,4]diazepine;

2-Methyl-4-(4-methyl-1-piperazinyl)- 10H-thieno[2,3-b][1,5]benzodiazepine LY-170053;

Chemical & Physical Properties:

Appearance: Yellowish crystalline powder

Assay :≥99.00%

Density: 1.32 g/cm3

Boiling Point: 462.6℃ at 760 mmHg

Melting Point: 195℃

Flash Point: 233.6℃

Refractive Index: 3.3

Storage Condition: Store in original container in a cool dark place.

Vapor Pressure: 0mmHg at 25℃

Safety Information:

Safety Statements: S22; S24/25

HS Code: 2934999090

WGK Germany: 3

A serotonin (5-HT2) and dopamine (D1/D2) receptor antagonist with anticholinergic activity. Antipsychotic. Olanzapine(LY170053) is a high affinity for 5-HT2 serotonin and D2 dopamine receptor antagonist.IC50 Value:Target: 5-HT ReceptorOlanzapine is a thienobenzodiazepine that blocks especially the serontonin (5-hydroxytryptamine [5-HT]) 5-HT2A and the dopamine D2 receptors (Ki values are 4 and 11 nM respectively) as well as muscarinic (M1), histamine (H1), 5-HT2C, 5-HT3 to 5-HT6, adrenergic (α(l)), and D4 receptors. Atypical antipsychotic for the treatment of schizophrenia. Olanzapine displays anticholinergic properties.

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