Fosinopril Sodium CAS 88889-14-9

Product Description:

Product Name: Fosinopril sodium CAS NO: 88889-14-9

Synonyms:

Fosinopril sodium;

sodium,(2S,4S)-4-cyclohexyl-1-[2-[(2-methyl-1-propanoyloxypropoxy)-(4-phenylbutyl)phosphoryl]acetyl]pyrrolidine-2-carboxylate;

Chemical & Physical Properties:

Appearance: White crystalline solid

Assay :≥99.00%

Density: 1.173

Boiling Point: 705.7℃at 760 mmHg

Melting Point: 196-198℃

Storage Condition: -20℃ Freezer

Safety Information:

HS Code: 2933990090

WGK Germany: 3

A phosphinic acid containing angiotensin converting enzyme (ACE) inhibitor. Antihypertensive. Fosinopril Sodium is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension and some types of chronic heart failure.Target: ACEFosinopril is a phosphinic acid-containing ester prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly hydrolyzed to fosinoprilat, its principle active metabolite. Fosinoprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Fosinopril may be used to treat mild to moderate hypertension, as an adjunct in the treatment of congestive heart failure, and to slow the rate of progression of renal disease in hypertensive individuals with diabetes mellitus and microalbuminuria or overt nephropathy.

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