Losartan Potassium CAS 124750-99-8 for Effective Blood Pressure Control

Product Description:

Product Name: Losartan potassium CAS NO: 124750-99-8

Synonyms:

Losartanpatassium;

potassium(2-butyl-4-chloro-1-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazol-5-yl)methanolate;

Chemical & Physical Properties:

Appearance: White to off-white crystalline power

Assay :≥99.00%

Density: 0.986 g/mL at 25℃(lit.)

Boiling Point: 682℃ at 760mmHg

Melting Point: 183.5-184.5℃ /Losartan/

Flash Point: 366.3℃

Refractive Index: n20/D 1.387(lit.)

Vapor Pressure: 1.55E-19mmHg at 25℃

Safety Information:

RTECS: NI6755100

Safety Statements: S26; S36/37/39

HS Code: 2933290090

Risk Statements: R36/37/38

Hazard Code: Xi

A nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive. As a angiotensin II receptor antagonist, Losartan Potassium is the potassium salt of losartan with antihypertensive activity, which is mainly used in the therapy of high blood pressure (hypertension) and diabetic nephropathy. It functions by relaxing blood vessels so that blood can flow more easily. It is also effective to help protect the kidneys from damage caused by diabetes and lower the risks of stroke in patients suffering from hypertension and myocardial enlargement. Besides, recent study has suggested that losartan is beneficial to reverse age related dysfunction in maintaining normal blood pressure and cellular energy usage on mitochondria and it can probably be used to treat left ventricular hypertrophy. It may also be used as an alternative agent for the treatment of systolic dysfunction, myocardial infarction, coronary artery disease, and heart failure.

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