Fexofenadine Hydrochloride CAS 153439-40-8 White to Beige Appearance

Product Description:

Product Name: Fexofenadine hydrochloride CAS NO: 153439-40-8

Synonyms:

Fexofenidine hydrochloride MDL 16455 hydrochloride Terfenidine carboxylate hydrochloride;

Fexofenadine HCl;

α,α-dimethyl-4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]benzeneacetic acid;

Chemical & Physical Properties:

Appearance: White to beige powder

Assay :≥99.00%

Melting Point: 148-150℃

Storage temp.: −20℃

Solubility: Soluble in Dimethyl sulfoxide (50 mM), and methanol.

Safety Information:

Hazard Code: Xi

Risk Statements: R36/37/38

Safety Statements: S26-36

WGK Germany: 3

HS Code: 2933399090

RTECS : CY1633377

The active metabolite of Terfenadine, a H1-histamine receptor antagonist. Fexofenadine hydrochloride (trade name: Allegra) belongs to a second-generation antihistamine pharmaceutical drug. It is mainly used for the treatment of allergy symptoms including watery eyes, hay fever, nasal congestion, urticaria, runny nose, itching eyes/nose, sneezing, hives, and itching. It is a kind of selectively peripheral H1 blocker. Its mechanism of action in vivo is through preventing the histamine-mediated activation of the H1 receptors, thus alleviating the symptoms related to allergy. Compared to the first-generation antihistamine drug, it is less prone to penetrate the blood-brain barrier, reducing the possibility to cause side effects such as drowsiness.

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