Foscarnet Sodium CAS 63585-09-1 for Treatment of Viral Infections

Product Description:

Product Name: Foscarnet sodium CAS NO: 63585-09-1

Synonyms:

Triapten;

Foscavir;

phosphonoformate sodium salt;

Chemical & Physical Properties:

Appearance: White or off-white crystalline powder

Assay :≥99.00%

Boiling Point: 490.7℃ at 760 mmHg

Melting Point: >250℃

Flash Point: 250.6℃

Storage Condition: Store in original container in a cool dark place.

Safety Information:

Safety Statements: S26; S36

HS Code: 2942000000

Packing Group: II

WGK Germany: 3

RIDADR: UN 2811 6.1/PG 3

Risk Statements: R36/37/38

Hazard Code: Xi

Foscarnet is the conjugate base of the chemical compound with the formula HO2CPO3H2. Foscarnet sodium is used as an antiviral medication. Foscarnet is the only antiviral approved by the FDA for the treatment of acyclovir-resistant HSV infections, a growing problem in the AIDS population. Foscarnet does not require HSV-encoded thymidine kinase. Foscarnet therapy reduces the healing time, pain, and viral shedding. It is administered intravenously, 40 mg/kg every 8 to 12 hours within 7 to 10 days in patients suspected of having acyclovir-resistant herpes simplex infection. Foscarnet is administered for 10 days. Associated side effects include azotemia secondary to nephrotoxicity, hyperphosphatemia, hypocalcemia, anemia, nausea, vomiting, and genital ulceration. Patients may eventually develop resistant strains. Preliminary trials indicate that topical 1%foscarnet cream may have some benefit for the treatment of acyclovir-resistant mucocutaneous HSV infection in patients with AIDS.

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