Pyrroloquinoline Quinone CAS 72909-34-3 for Improved Cognition

Product Description:

Product Name: Pyrroloquinoline quinone CAS NO: 72909-34-3

Synonyms:

4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid;

2,7,9-Tricarboxy-1H-pyrrolo(2,3-f)quinoline-4,5-dione;

Coenzyme PQQ;

Chemical & Physical Properties:

Appearance: Orange-Red Solid

Assay :≥99.00%

Density: 1.963 g/cm3

Boiling Point: 1018.6℃ at 760 mmHg

Refractive Index: 1.801

Stability: Light and Temperature Sensitive

Storage Condition: 2-8℃

Safety Information:

Safety Statements: S22-24/25

WGK Germany: 3

F: 8

HS Code: 29339900

Pyrroloquinoline quinone (PQQ) was discovered by J.G. Hauge as the third redox cofactor after nicotinamide and flavin in bacteria (although he hypothesised that it was naphthoquinone). Anthony and Zatman also found the unknown redox cofactor in alcohol dehydrogenase. In 1979, Salisbury and colleagues as well as Duine and colleagues extracted this prosthetic group from methanol dehydrogenase of methylotrophs and identified its molecular structure. Adachi and colleagues identified that PQQ was also found in Acetobacter.

These enzymes containing PQQ are called quinoproteins. Glucose dehydrogenase, one of the quinoproteins, is used as a glucose sensor. Subsequently, PQQ was found to stimulate growth in bacteria. In addition, antioxidant and neuroprotective effects were also found.

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