BENZBROMARONE CAS 3562-84-3 With Molecular Weight 424.08300

Product Description:

Product Name: BENZBROMARONE CAS NO: 3562-84-3

Synonyms:

3-(3,5-Dibromo-4-hydroxybenzoyl)-2-ethylbenzofuran;

(3,5-dibromo-4-hydroxyphenyl)(2-ethylbenzofuran-3-yl)methanone;

2-Ethyl-3-(3,5-dibromo-4-hydroxybenzoyl)benzofuran;

Chemical & Physical Properties:

Appearance: White to off-white crystalline powder

Assay :≥99.00%

Density: 1.709 g/cm3

Melting Point: 161 – 163℃

Flash Point: 264.7℃

Storage Condition: 2-8℃

Solubility: Practically insoluble in water, freely soluble in ace-tone and in methylene chloride, sparingly soluble in ethanol (96 per cent).

Safety Information:

Hazard Class: 6.1(b)

Safety Statement: S36

HS Code: 2932190090

Packing Group: III

RIDADR: UN 2811

Risk Statement: R22

Hazard Code: Xn

Benzbromarone (INN) is a uricosuric agent and non-competitive inhibitor of xanthine oxidase used in the treatment of gout, especially when allopurinol, a first-line treatment, fails or produces intolerable adverse effects. It is structurally related to the antiarrhythmic amiodarone.

Benzbromarone is highly effective and well tolerated, and clinical trials as early as 1981 and as recently as April 2008 have suggested it is superior to both allopurinol, a xanthine oxidase inhibitor but not uricosuric, and probenecid, another uricosuric drug.

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