Cefotaxime Acid CAS 63527-52-6

Product Description:

Product Name: Cefotaxime acid CAS NO: 63527-52-6                       

Synonyms:

Zariviz;

Cefabol;

Cefotaxime;

Chemical & Physical Properties:

Appearance: White power

Assay :≥99.0%

Density: 1.8 g/cm3

Refractive Index: 1.778

Safety Information:

HS Code: 3003201100

RTECS: XI0240000

Cefotaxime (INN) is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, cefotaxime is a broad-spectrum antibiotic with activity against numerous gram-positive and gram-negative bacteria. Developed by Hoechst-Roussel Pharmaceuticals in the late 1980s, it was among the first third-generation ("extended spectrum") cephalosporins and the first of its class to become available in the United States. It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.

Cefotaxime has a broad spectrum of antibicrobial use. It acts bactericidally. It is highly active with respect to Gram-negative microorganisms (E. coli, Citrobacter, Proteus mirabilis, P. indole, Providencia, Klebsiella, Serratia), and a few strains of Pseudomonas, H. influenzae that are resistant to other antibiotics. Cefotaxime is less active with respect to streptococci, pneumococci, meningococci, gonococci, and bacteroides. It is resistant to the majority of beta-lacatamases of Gram-positive and Gram-negative microorganisms.

This drug is used for severe bacterial infections caused by microorganisms that are sen[1]sitive to the drug such as peritonitis, sepsis, abdominal infections, infections of the pelvis minor, infections of the lower respiratory tract, urinary tract, bones, joints, skin, soft tissues, and infected wounds and burns. Synonyms of this drug are claforan, zarivis, and others.

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